The decor and ambience are as classy as you'll find. Chairs are comfy. Atmosphere is more subdued than the Venetian, more "golf clap" than "football cheering". Tough to think of a nicer place to play.
The 2/5 NL game seemed to have a lot of regulars, and played fairly tough/tight. The 1/3 NL game was tougher than average for Vegas. Both the 1/4 and 2/5 can be profitable, but you'll want to bring your A-game and not expect an everlasting stream of fish like some other rooms. There were still plenty of donks, however, just a classier level of donks.
Technically speaking, the dealers are as good as you'll find. Personality-wise, some are a bit stiff, but some are friendly. If you're looking for a wise-cracking personality (which I like), you won't find one dealing here; it is a "professional" attitude all the way (not a bad thing, just part of the overall room atmosphere).
Premium drinks, regular rounds, pretty good speed. I don't grade on attractiveness, but for those who do, you won't be disappointed.
Management did pretty well given the room size and number of tables in play. However, list manager seemed a bit arrogant (apparently the 1/3 & 2/5 NL players are not as important as the bigger game players), and my request for a table change was ignored until I made a second request.
Compared to the other "big" rooms, Wynn does fairly well, offering a good poker room rate and hourly comps. No jackpots, but then again, you save on the jackpot drop.